Just in a few step...

At walking distance you can reach the Vatican City (the Vatican Gardens, the Vatican Museums and St. Peter Church) and the St. Angel Castle are no more than 15/25 minutes walking from the B&B.

Other major tourist attractions can be reached by public transportation:

Colosseum, Piazza Navona, Piazza Venezia, "Trinità dei Monti" (Spanish Steps), Pantheon, Villa Borghese, Ara Coeli, S. Pietro in Vincoli, Trevi Fountain and much much more...